Antibiotics | Free Full-Text | Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening
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IJMS | Free Full-Text | No Substrate Left behind—Mining of Shotgun Proteomics Datasets Rescues Evidence of Proteolysis by SARS-CoV-2 3CLpro Main Protease
Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition | Nature Chemical Biology
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Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor | ACS Medicinal Chemistry Letters
De novo design of discrete, stable 310-helix peptide assemblies | Nature
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes | Scientific Reports
Surrogate Based Genetic Algorithm Method for Efficient Identification of Low-Energy Peptide Structures | Journal of Chemical Theory and Computation
Unprotected peptide macrocyclization and stapling via a fluorine-thiol displacement reaction | Nature Communications
IJMS | Free Full-Text | Modeling SILAC Data to Assess Protein Turnover in a Cellular Model of Diabetic Nephropathy
Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology | Nature Communications
Lys-C/Arg-C, a More Specific and Efficient Digestion Approach for Proteomics Studies | Analytical Chemistry
Ultrafast Two-Dimensional Infrared Spectroscopy Resolved a Structured Lysine 159 on the Cytoplasmic Surface of the Microbial Photoreceptor Bacteriorhodopsin | Journal of the American Chemical Society
Getting in Shape: Controlling Peptide Bioactivity and Bioavailability Using Conformational Constraints | ACS Chemical Biology
Rational Discovery of Microtubule-Stabilizing Peptides | Journal of Chemical Information and Modeling
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Association of mitochondrial DNA content, heteroplasmies and inter-generational transmission with autism | Nature Communications
Accelerating the Validation of Endogenous On-Target Engagement and In Cellulo Kinetic Assessment for Covalent Inhibitors of KRASG12C in Early Drug Discovery | ACS Chemical Biology
Experimental and Theoretical Observation of Different Intramolecular H-bonds in Lysine Conformations | The Journal of Physical Chemistry B
Synthesis of Vaniprevir (MK-7009): Lactamization To Prepare a 22-Membered Macrocycle | The Journal of Organic Chemistry
Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains | Biochemistry