Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience
Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns | Journal of Chemical Information and Modeling
Recent Advances in the Development of Sigma Receptor Ligands as Cytotoxic Agents: A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect
Frontiers | The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia
A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus | NEJM
The blocking of kappa‐opioid receptor reverses the changes in dorsolateral striatum dopamine dynamics during the amphetamine sensitization - Azocar - 2019 - Journal of Neurochemistry - Wiley Online Library
Antinociceptive and Analgesic Effects of (2R,6R)-Hydroxynorketamine | Journal of Pharmacology and Experimental Therapeutics
Antagonists of the kappa opioid receptor - ScienceDirect
Discovery of the First N-Substituted 4β-Methyl-5-(3-hydroxyphenyl)morphan To Possess Highly Potent and Selective Opioid δ Receptor Antagonist Activity | Journal of Medicinal Chemistry
Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics | Hypertension
Conformational Constraint between Aromatic Residue Side Chains in the “Message” Sequence of the Peptide Arodyn Using Ring Closing Metathesis Results in a Potent and Selective Kappa Opioid Receptor Antagonist | Journal of
Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local Neurotransmission and Conditioned Place Aversion | Neuropsychopharmacology
Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior | Neuropsychopharmacology
Frontiers | Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966
Nanobody-enabled monitoring of kappa opioid receptor states | Nature Communications
Molecules | Free Full-Text | Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents
κ-opioid receptor - Wikipedia
Pharmaceuticals | Free Full-Text | Opioid Analgesia and Opioid-Induced Adverse Effects: A Review
Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors
Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens | Neuropsychopharmacology
