![New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/jm901137j/asset/images/large/jm-2009-01137j_0011.jpeg)
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry
![New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/jm901137j/asset/images/medium/jm-2009-01137j_0007.gif)
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry
![Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S. Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S.](https://journals.sagepub.com/cms/10.1177/2472555218768497/asset/images/large/10.1177_2472555218768497-fig2.jpeg)
Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S.
![New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/jm901137j/asset/images/large/jm-2009-01137j_0002.jpeg)
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry
![Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S221138352100071X-gr3.jpg)
Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect
![Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S221138352100071X-gr5.jpg)
Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect
![PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dc74cc019e30ea0cba35ca71c2e5ca1bc731e89b/2-Table1-1.png)
PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar
![Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology](https://pubs.acs.org/cms/10.1021/acschembio.7b00903/asset/images/medium/cb-2017-00903z_0006.gif)
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology
![Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology](https://pubs.acs.org/cms/10.1021/acschembio.7b00903/asset/images/large/cb-2017-00903z_0008.jpeg)
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology
![Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology](https://pubs.acs.org/cms/10.1021/acschembio.7b00903/asset/images/medium/cb-2017-00903z_0005.gif)
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology
![Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S221138352100071X-gr2.jpg)
Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands - ScienceDirect
![Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2472555222068800-gr4.jpg)
Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect
![Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology](https://pubs.acs.org/cms/10.1021/acschembio.7b00903/asset/images/large/cb-2017-00903z_0001.jpeg)
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology
![Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology](https://pubs.acs.org/cms/10.1021/acschembio.7b00903/asset/images/large/cb-2017-00903z_0003.jpeg)
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations | ACS Chemical Biology
![PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dc74cc019e30ea0cba35ca71c2e5ca1bc731e89b/7-Table9-1.png)
PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar
![Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2472555222068800-gr3.jpg)
Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - ScienceDirect
![New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/jm901137j/asset/images/medium/jm-2009-01137j_0012.gif)
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry
![Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S. Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S.](https://journals.sagepub.com/cms/10.1177/2472555218768497/asset/images/large/10.1177_2472555218768497-fig1.jpeg)
Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection - Subhas J. Chakravorty, James Chan, Marie Nicole Greenwood, Ioana Popa-Burke, Katja S. Remlinger, Stephen D. Pickett, Darren V. S.
![PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dc74cc019e30ea0cba35ca71c2e5ca1bc731e89b/3-Table3-1.png)
PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar
![New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry](https://pubs.acs.org/cms/10.1021/jm901137j/asset/images/large/jm-2009-01137j_0010.jpeg)
New Substructure Filters for Removal of Pan Assay Interference Compounds ( PAINS) from Screening Libraries and for Their Exclusion in Bioassays | Journal of Medicinal Chemistry
![PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dc74cc019e30ea0cba35ca71c2e5ca1bc731e89b/9-Table11-1.png)
PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar
![PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar PDF] New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/dc74cc019e30ea0cba35ca71c2e5ca1bc731e89b/12-Figure6-1.png)